Source Themes

Host-to-Pathogen Transfer of Neutrophil Components via Extracellular Vesicles Shields Candida albicans from Immune Attack in Human Blood
In tissues, neutrophils neutralize Candida albicans through phagocytosis and delay C. albicans hyphae growth by deploying neutrophil …
PDF DOI
Characterization of tRNA ligase function in pathogenic fungi and trypanosomes reveals the ligase domain as a promising drug target
The majority of eukaryotes encode some intron-containing pre-tRNAs. Splicing of these pre-tRNAs requires a dedicated tRNA splicing …
PDF DOI
The Small RNA MicC is a Multifunctional Regulator of Extraintestinal Pathogenic Escherichia coli Fitness across Multiple Host Niches
Small non-coding RNAs (sRNA) modulate diverse bacterial functions ranging from carbon metabolism to virulence gene expression. Previous …
PDF DOI
Advances in molecular tools for elucidating nucleic acid biology in fungal pathogens
Throughout the history of molecular biology, surprising advances have come from the study of all sorts of microbes. The first …
PDF DOI
An Improved Description of the Small RNA Landscape of the Human Fungal Pathogen Aspergillus fumigatus
Aspergillus fumigatus is a ubiquitous filamentous fungus and dangerous human pathogen that produces a limited pool of small RNAs under …
PDF DOI
Comprehensive mapping of the 5' and 3' untranslated regions of Aspergillus fumigatus reveals diverse mechanisms of mRNA processing including premature transcription termination
In the twenty years since the first genome sequencing of Aspergillus fumigatus, the field has seen an explosion in both the number of …
PDF DOI
tRNA hypomodification facilitates 5-fluorocytosine resistance via cross-pathway control system activation in Aspergillus fumigatus.
Increasing antifungal drug resistance is a major concern associated with human fungal pathogens like Aspergillus fumigatus. Genetic …
PDF DOI
Past, Present, and Future of RNA Modifications in Infectious Disease Research
In early 2024, the National Academies of Sciences, Engineering, and Medicine (NASEM) released a roadmap for the future of research into …
DOI
Tracking the uptake of labelled host-derived extracellular vesicles by the human fungal pathogen Aspergillus fumigatus
Extracellular vesicles (EVs) have gained attention as facilitators of intercellular as well as interkingdom communication during …
DOI
RNA-Biologie von Pilzinfektionen
DOI